Studies on the Dual Requirement for Phenylalanine and Tyrosine in Tissue Cultures
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چکیده
منابع مشابه
Studies on the dual requirement for phenylalanine and tyrosine in tissue cultures.
Studies in several laboratories (l-4) have established that isolated tissues growing or surviving in vitro require both phenylalanine and tyrosine. This finding is in marked contrast to the well known sparing effect of tyrosine on the phenylalanine requirement of the whole animal (5-7). In the latter case, this sparing effect has been attributed (8) to the action of “phenylalanine hydroxylase,”...
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15 صفحه اولOn the metabolism of phenylalanine and tyrosine.
The metabolism of phenylalanine and tyrosine has been the subject of investigation for many years. Much evidence has been produced to show that in mammalian tissue phenylalanine is converted to tyrosine (l-5). Tyrosine can be oxidized to p-hydroxyphenylpyruvic acid, which can in turn form homogentisic acid (5-13). Embden, Salomon, and Schmidt (14) showed that phenylalanine, tyrosine, and homoge...
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ژورنال
عنوان ژورنال: Journal of Biological Chemistry
سال: 1959
ISSN: 0021-9258
DOI: 10.1016/s0021-9258(18)69762-5